Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 04/03/22 21:00 | 04/03/22 21:00 | Deportivo Alaves | FC Séville | 0-0 | 2 - 5 points |
| 05/03/22 14:00 | 05/03/22 14:00 | CA Osasuna | Villarreal CF | 1-0 | 2 - 5 points |
| 05/03/22 16:15 | 05/03/22 16:15 | Espanyol Barcelone | FC Getafe | 2-0 | 2 - 5 points |
| 05/03/22 18:30 | 05/03/22 18:30 | Valence CF | Granada CF | 3-1 | 2 - 5 points |
| 05/03/22 21:00 | 05/03/22 21:00 | Real Madrid | Real Sociedad | 4-1 | 2 - 5 points |
| 06/03/22 14:00 | 06/03/22 14:00 | FC Cadiz | Rayo Vallecano | 2-0 | 2 - 5 points |
| 06/03/22 16:15 | 06/03/22 16:15 | FC Elche | FC Barcelone | 1-2 | 2 - 5 points |
| 06/03/22 18:30 | 06/03/22 18:30 | Celta Vigo | RCD Majorque | 4-3 | 2 - 5 points |
| 06/03/22 21:00 | 06/03/22 21:00 | Bétis Séville | Atletico Madrid | 1-3 | 2 - 5 points |
| 07/03/22 21:00 | 07/03/22 21:00 | Athletic Bilbao | UD Levante | 3-1 | 2 - 5 points |