Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 11/09/21 18:30 | 11/09/21 18:30 | UD Levante | Rayo Vallecano | 1-1 | 2 - 5 points |
| 11/09/21 21:00 | 11/09/21 21:00 | Athletic Bilbao | RCD Majorque | 2-0 | 2 - 5 points |
| 12/09/21 14:00 | 12/09/21 14:00 | Espanyol Barcelone | Atletico Madrid | 1-2 | 2 - 5 points |
| 12/09/21 16:15 | 12/09/21 16:15 | CA Osasuna | Valence CF | 1-4 | 2 - 5 points |
| 12/09/21 18:30 | 12/09/21 18:30 | FC Cadiz | Real Sociedad | 0-2 | 2 - 5 points |
| 12/09/21 21:00 | 12/09/21 21:00 | Real Madrid | Celta Vigo | 5-2 | 2 - 5 points |
| 13/09/21 20:00 | 13/09/21 20:00 | FC Getafe | FC Elche | 0-1 | 2 - 5 points |
| 13/09/21 22:00 | 13/09/21 22:00 | Granada CF | Bétis Séville | 1-2 | 2 - 5 points |
| 21/12/21 19:00 | 21/12/21 19:00 | Villarreal CF | Deportivo Alaves | 5-2 | 2 - 5 points |
| 21/12/21 21:30 | 21/12/21 21:30 | FC Séville | FC Barcelone | 1-1 | 2 - 5 points |