Calendrier
| Compétition | Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|---|
| DFB | 26/10/21 18:30 | 26/10/21 18:30 | Preußen Münster | Hertha BSC | 1-3 | 2 - 5 points |
| DFB | 26/10/21 18:30 | 26/10/21 18:30 | SV Babelsberg 03 | RB Leipzig | 0-1 | 2 - 5 points |
| DFB | 26/10/21 18:30 | 26/10/21 18:30 | TSV 1860 München | FC Schalke 04 | 1-0 | 2 - 5 points |
| DFB | 26/10/21 18:30 | 26/10/21 18:30 | 1899 Hoffenheim | Holstein Kiel | 5-1 | 2 - 5 points |
| DFB | 26/10/21 20:00 | 26/10/21 20:00 | Borussia Dortmund | FC Ingolstadt | 2-0 | 2 - 5 points |
| DFB | 26/10/21 20:45 | 26/10/21 20:45 | 1. FC Nürnberg | Hamburger SV | 3-5a.TAB | 2 - 5 points |
| DFB | 26/10/21 20:45 | 26/10/21 20:45 | FSV Mayence 05 | Arminia Bielefeld | 3-2a.Prlg | 2 - 5 points |
| DFB | 26/10/21 20:45 | 26/10/21 20:45 | VfL Osnabrück | SC Freiburg | 4-5a.TAB | 2 - 5 points |
| DFB | 27/10/21 18:30 | 27/10/21 18:30 | Dynamo Dresden | FC St. Pauli | 2-3a.Prlg | 2 - 5 points |
| DFB | 27/10/21 18:30 | 27/10/21 18:30 | SV Waldhof Mannheim | 1. FC Union Berlin | 1-3a.Prlg | 2 - 5 points |
| DFB | 27/10/21 18:30 | 27/10/21 18:30 | Bayer 04 Leverkusen | Karlsruher SC | 1-2 | 2 - 5 points |
| DFB | 27/10/21 18:30 | 27/10/21 18:30 | VfL Bochum | FC Augsburg | 7-6a.TAB | 2 - 5 points |
| DFB | 27/10/21 20:45 | 27/10/21 20:45 | Bor. Mönchengladbach | Bayern Munich | 5-0 | 2 - 5 points |
| DFB | 27/10/21 20:45 | 27/10/21 20:45 | Hannover 96 | Fortuna Düsseldorf | 3-0 | 2 - 5 points |
| DFB | 27/10/21 20:45 | 27/10/21 20:45 | Jahn Regensburg | FC Hansa Rostock | 5-7a.TAB | 2 - 5 points |
| DFB | 27/10/21 20:45 | 27/10/21 20:45 | VfB Stuttgart | 1. FC Cologne | 0-2 | 2 - 5 points |