Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 28/08/21 13:30 | 28/08/21 13:29 | Manchester City | FC Arsenal | 5-0 | 2 - 4 points |
| 28/08/21 16:00 | 28/08/21 15:59 | Newcastle United | FC Southampton | 2-2 | 2 - 4 points |
| 28/08/21 16:00 | 28/08/21 15:59 | Norwich City | Leicester City | 1-2 | 2 - 4 points |
| 28/08/21 16:00 | 28/08/21 15:59 | West Ham United | Crystal Palace | 2-2 | 2 - 4 points |
| 28/08/21 16:00 | 28/08/21 15:59 | Aston Villa | Brentford FC | 1-1 | 2 - 4 points |
| 28/08/21 16:00 | 28/08/21 15:59 | Brighton and Hove Albion | FC Everton | 0-2 | 2 - 4 points |
| 28/08/21 18:30 | 28/08/21 18:29 | FC Liverpool | FC Chelsea | 1-1 | 2 - 4 points |
| 29/08/21 15:00 | 29/08/21 14:59 | Tottenham Hotspur | FC Watford | 1-0 | 2 - 4 points |
| 29/08/21 15:00 | 29/08/21 14:59 | FC Burnley | Leeds United | 1-1 | 2 - 4 points |
| 29/08/21 17:30 | 29/08/21 17:29 | Wolverhampton Wanderers | Manchester United | 0-1 | 2 - 4 points |