Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 22/10/21 21:00 | 22/10/21 20:59 | FC Arsenal | Aston Villa | 3-1 | 2 - 4 points |
| 23/10/21 13:30 | 23/10/21 13:29 | FC Chelsea | Norwich City | 7-0 | 2 - 4 points |
| 23/10/21 16:00 | 23/10/21 15:59 | Crystal Palace | Newcastle United | 1-1 | 2 - 4 points |
| 23/10/21 16:00 | 23/10/21 15:59 | FC Everton | FC Watford | 2-5 | 2 - 4 points |
| 23/10/21 16:00 | 23/10/21 15:59 | Leeds United | Wolverhampton Wanderers | 1-1 | 2 - 4 points |
| 23/10/21 16:00 | 23/10/21 15:59 | FC Southampton | FC Burnley | 2-2 | 2 - 4 points |
| 23/10/21 18:30 | 23/10/21 18:29 | Brighton and Hove Albion | Manchester City | 1-4 | 2 - 4 points |
| 24/10/21 15:00 | 24/10/21 14:59 | Brentford FC | Leicester City | 1-2 | 2 - 4 points |
| 24/10/21 15:00 | 24/10/21 14:59 | West Ham United | Tottenham Hotspur | 1-0 | 2 - 4 points |
| 24/10/21 17:30 | 24/10/21 17:29 | Manchester United | FC Liverpool | 0-5 | 2 - 4 points |