Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 22/01/22 18:45 | 22/01/22 18:45 | Vitesse Arnheim | FC Groningen | 1-3 | 2 - 4 points |
| 22/01/22 20:00 | 22/01/22 20:00 | AZ Alkmaar | Cambuur-Leeuwarden | 0-0 | 2 - 4 points |
| 22/01/22 20:00 | 22/01/22 20:00 | SC Heerenveen | PEC Zwolle | 0-1 | 2 - 4 points |
| 22/01/22 21:00 | 22/01/22 21:00 | Willem II Tilburg | FC Twente Enschede | 0-1 | 2 - 4 points |
| 23/01/22 12:15 | 23/01/22 12:15 | NEC Nijmwegen | Feyenoord Rotterdam | 1-4 | 2 - 4 points |
| 23/01/22 14:30 | 23/01/22 14:30 | PSV Eindhoven | Ajax Amsterdam | 1-2 | 2 - 4 points |
| 23/01/22 14:30 | 23/01/22 14:30 | Heracles Almelo | Go Ahead Eagles Deventer | 1-1 | 2 - 4 points |
| 23/01/22 16:45 | 23/01/22 16:45 | Sparta Rotterdam | FC Utrecht | 0-3 | 2 - 4 points |
| 23/01/22 20:00 | 23/01/22 20:00 | RKC Waalwijk | Fortuna Sittard | 2-1 | 2 - 4 points |