Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 18/03/22 18:30 | 18/03/22 18:30 | FC St. Pauli | 1. FC Heidenheim 1846 | 1-0 | 2 - 5 points |
| 18/03/22 18:30 | 18/03/22 18:30 | Erzgebirge Aue | Karlsruher SC | 0-3 | 2 - 5 points |
| 19/03/22 13:30 | 19/03/22 13:30 | FC Schalke 04 | Hannover 96 | 2-1 | 2 - 5 points |
| 19/03/22 13:30 | 19/03/22 13:30 | Fortuna Düsseldorf | Hamburger SV | 1-1 | 2 - 5 points |
| 19/03/22 13:30 | 19/03/22 13:30 | SV Sandhausen | FC Hansa Rostock | 0-1 | 2 - 5 points |
| 19/03/22 20:30 | 19/03/22 20:30 | Werder Bremen | SV Darmstadt 98 | 1-0 | 2 - 5 points |
| 20/03/22 13:30 | 20/03/22 13:30 | Holstein Kiel | FC Ingolstadt | 1-0 | 2 - 5 points |
| 20/03/22 13:30 | 20/03/22 13:30 | 1. FC Nürnberg | Dynamo Dresden | 1-1 | 2 - 5 points |
| 20/03/22 13:30 | 20/03/22 13:30 | Jahn Regensburg | SC Paderborn 07 | 1-0 | 2 - 5 points |