Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 16/12/21 21:00 | 16/12/21 21:00 | Valenciennes FC | Racing Club Strasbourg | 0-1 | 9 - 10 - 3 |
| 17/12/21 21:00 | 17/12/21 21:00 | Paris FC | Olympique Lyonnais | 0-0 | 10 - 10 - 3 |
| 18/12/21 13:45 | 18/12/21 13:45 | Sarre-Union | FC Versailles 78 | 0-1 | 6 - 10 - 3 |
| 18/12/21 13:45 | 18/12/21 13:45 | AS Panazol | AS Vitre | 4-5a.TAB | 5 - 10 - 3 |
| 18/12/21 13:45 | 18/12/21 13:45 | ES Troyes AC | AS Nancy-Lorraine | 3-5a.TAB | 3 - 10 - 9 |
| 18/12/21 13:45 | 18/12/21 13:45 | Toulouse FC | Nîmes Olympique | 4-1 | 3 - 10 - 7 |
| 18/12/21 13:45 | 18/12/21 13:45 | FC Hauts Lyonnais | SC Bastia | 1-3 | 7 - 10 - 3 |
| 18/12/21 16:00 | 18/12/21 16:00 | Jura Sud | Saint-Denis FC | 5-2 | 3 - 10 - 6 |
| 18/12/21 16:00 | 18/12/21 16:00 | En Avant Guingamp | Amiens SC | 2-3 | 3 - 10 - 6 |
| 18/12/21 16:00 | 18/12/21 16:00 | JS Chemin Bas d'Avignon | Clermont Foot | 0-4 | 10 - 10 - 3 |
| 18/12/21 16:00 | 18/12/21 16:00 | FC Sochaux-Montbéliard | FC Nantes | 4-5a.TAB | 9 - 10 - 3 |
| 18/12/21 16:00 | 18/12/21 16:00 | US Créteil-Lusitanos | Venissieux FC | 3-0 | 4 - 10 - 5 |
| 18/12/21 18:30 | 18/12/21 18:30 | Cannes | Dijon FCO | 4-3a.TAB | 6 - 10 - 3 |
| 18/12/21 18:30 | 18/12/21 18:30 | US Quevilly Rouen | Stade Lavallois | 5-3a.TAB | 3 - 10 - 7 |
| 18/12/21 18:30 | 18/12/21 18:30 | Thaon | Beauvais AS | 7-5a.TAB | 4 - 10 - 4 |
| 18/12/21 18:30 | 18/12/21 18:30 | LOSC Lille | AJ Auxerre | 3-1 | 3 - 10 - 10 |
| 18/12/21 21:00 | 18/12/21 21:00 | Stade Rennais FC | FC Lorient | 1-0 | 3 - 10 - 10 |
| 19/12/21 13:45 | 19/12/21 13:45 | Bergerac Perigord FC | FC Metz | 5-4a.TAB | 7 - 10 - 3 |
| 19/12/21 13:45 | 19/12/21 13:45 | Red Star FC | AS Monaco | 0-2 | 10 - 10 - 3 |
| 19/12/21 13:45 | 19/12/21 13:45 | Stade Poitevin FC | RC Lens | 0-1 | 10 - 10 - 3 |
| 19/12/21 13:45 | 19/12/21 13:45 | Olympique de Marseille | ES Cannet Rocheville | 4-1 | 3 - 10 - 7 |
| 19/12/21 13:45 | 19/12/21 13:45 | Lyon La Duchere | AS St. Etienne | 0-1 | 6 - 10 - 3 |
| 19/12/21 16:00 | 19/12/21 16:00 | Reims Sainte-Anne | Stade de Reims | 0-1 | 10 - 10 - 3 |
| 19/12/21 16:00 | 19/12/21 16:00 | Linas Montlhery | Angers SCO | 2-0 | 10 - 10 - 3 |
| 19/12/21 16:00 | 19/12/21 16:00 | Andrézieux-Bouthéon FC | Montpellier Hérault SC | 0-1 | 10 - 10 - 3 |
| 19/12/21 16:00 | 19/12/21 16:00 | ES Wasquehal | Vannes OC | 0-4 | 4 - 10 - 4 |
| 19/12/21 18:20 | 19/12/21 18:20 | US Montauban | Vendee La Roche sur Yon | 1-2 | 4 - 10 - 5 |
| 19/12/21 18:20 | 19/12/21 18:20 | Girondins de Bordeaux | Jumeaux M'Zouasia | 10-0 | 3 - 10 - 10 |
| 19/12/21 18:20 | 19/12/21 18:20 | Dinan-Lehon | Stade Brestois 29 | 12-13a.TAB | 10 - 10 - 3 |
| 19/12/21 18:20 | 19/12/21 18:20 | US Chauvigny | Chartres FC | 2-1 | 4 - 10 - 4 |
| 19/12/21 18:20 | 19/12/21 18:20 | SO Cholet | OGC Nice | 0-1 | 10 - 10 - 3 |
| 19/12/21 21:10 | 19/12/21 21:10 | Feignies Aulnoye | Paris Saint-Germain | 0-3 | 10 - 10 - 3 |