| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|
| 11/02/22 20:30 | 11/02/22 20:00 | RB Leipzig | 1. FC Cologne | 3-1 | 2 - 4 points |
| 12/02/22 15:30 | 12/02/22 15:00 | Bor. Mönchengladbach | FC Augsburg | 3-2 | 2 - 4 points |
| 12/02/22 15:30 | 12/02/22 15:00 | Eintracht Frankfurt | VfL Wolfsburg | 0-2 | 2 - 4 points |
| 12/02/22 15:30 | 12/02/22 15:00 | SpVgg Greuther Fürth | Hertha BSC | 2-1 | 2 - 4 points |
| 12/02/22 15:30 | 12/02/22 15:00 | VfL Bochum | Bayern Munich | 4-2 | 2 - 4 points |
| 12/02/22 15:30 | 12/02/22 15:00 | SC Freiburg | FSV Mayence 05 | 1-1 | 2 - 4 points |
| 12/02/22 18:30 | 12/02/22 18:00 | Bayer 04 Leverkusen | VfB Stuttgart | 4-2 | 2 - 4 points |
| 13/02/22 15:30 | 13/02/22 15:00 | 1. FC Union Berlin | Borussia Dortmund | 0-3 | 2 - 4 points |
| 13/02/22 17:30 | 13/02/22 17:00 | 1899 Hoffenheim | Arminia Bielefeld | 2-0 | 2 - 4 points |
