Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 29/01/22 14:00 | 29/01/22 14:00 | Bonner SC | SC Wiedenbrück | 0-0 | 2 - 4 points |
| 29/01/22 14:00 | 29/01/22 14:00 | FC Schalke 04 II | Sportfreunde Lotte | 4-1 | 2 - 4 points |
| 29/01/22 14:00 | 29/01/22 14:00 | Preußen Münster | FC Wegberg-Beeck | 1-0 | 2 - 4 points |
| 29/01/22 14:00 | 29/01/22 14:00 | SV Lippstadt 08 | Bor. Mönchengladbach II | 0-1 | 2 - 4 points |
| 29/01/22 14:00 | 29/01/22 14:00 | KFC Uerdingen | 1. FC Cologne II | 2-2 | 2 - 4 points |
| 15/02/22 19:30 | 15/02/22 19:30 | Fortuna Düsseldorf II | Rot-Weiss Ahlen | 1-1 | 2 - 4 points |
| 02/03/22 19:30 | 02/03/22 19:30 | VfB Homberg | SV Rödinghausen | 0-1 | 2 - 4 points |
| 09/03/22 19:00 | 09/03/22 19:00 | Wuppertaler SV | SV Straelen | 2-1 | 2 - 4 points |
| 16/03/22 19:30 | 16/03/22 19:30 | Rot-Weiss Oberhausen | Alemannia Aachen | 2-1 | 2 - 4 points |
| 16/03/22 19:45 | 16/03/22 19:45 | SC Fortuna Cologne | Rot-Weiss Essen | 3-3 | 2 - 4 points |