Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 05/02/22 14:00 | 05/02/22 14:00 | Alemannia Aachen | KFC Uerdingen | 3-2 | 2 - 4 points |
| 05/02/22 14:00 | 05/02/22 14:00 | FC Wegberg-Beeck | FC Schalke 04 II | 1-4 | 2 - 4 points |
| 05/02/22 14:00 | 05/02/22 14:00 | 1. FC Cologne II | SC Wiedenbrück | 0-0 | 2 - 4 points |
| 05/02/22 14:00 | 05/02/22 14:00 | SV Straelen | SC Fortuna Cologne | 0-2 | 2 - 4 points |
| 05/02/22 14:00 | 05/02/22 14:00 | Rot-Weiss Ahlen | VfB Homberg | 3-3 | 2 - 4 points |
| 05/02/22 14:00 | 05/02/22 14:00 | Bor. Mönchengladbach II | Rot-Weiss Oberhausen | 0-3 | 2 - 4 points |
| 06/02/22 14:00 | 06/02/22 14:00 | Rot-Weiss Essen | Fortuna Düsseldorf II | 4-1 | 2 - 4 points |
| 23/02/22 19:30 | 23/02/22 19:30 | SV Rödinghausen | Preußen Münster | 1-0 | 2 - 4 points |
| 16/03/22 19:00 | 16/03/22 19:00 | Wuppertaler SV | Bonner SC | 0-3 | 2 - 4 points |
| 16/03/22 19:30 | 16/03/22 19:30 | Sportfreunde Lotte | SV Lippstadt 08 | 0-2 | 2 - 4 points |