Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 05/03/22 14:00 | 05/03/22 14:00 | SV Rödinghausen | KFC Uerdingen | 0-1 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | SC Fortuna Cologne | VfB Homberg | 1-1 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | Bor. Mönchengladbach II | Alemannia Aachen | 3-2 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | Sportfreunde Lotte | 1. FC Cologne II | 1-1 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | Rot-Weiss Ahlen | Rot-Weiss Oberhausen | 0-0 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | SV Straelen | FC Schalke 04 II | 2-1 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | Fortuna Düsseldorf II | Bonner SC | 1-2 | 2 - 4 points |
| 05/03/22 14:00 | 05/03/22 14:00 | FC Wegberg-Beeck | SC Wiedenbrück | 1-0 | 2 - 4 points |
| 06/03/22 14:00 | 06/03/22 14:00 | Wuppertaler SV | Preußen Münster | 1-1 | 2 - 4 points |
| 19/04/22 19:30 | 19/04/22 19:30 | Rot-Weiss Essen | SV Lippstadt 08 | 4-0 | 2 - 4 points |