Calendrier
| Date | Clôture des pronostics | À domicile | A l'extérieur | Résultat | Règle des points |
|---|---|---|---|---|---|
| 11/03/22 19:00 | 11/03/22 19:00 | SC Wiedenbrück | SV Rödinghausen | 1-2 | 2 - 4 points |
| 12/03/22 14:00 | 12/03/22 14:00 | Alemannia Aachen | Sportfreunde Lotte | 1-0 | 2 - 4 points |
| 12/03/22 14:00 | 12/03/22 14:00 | VfB Homberg | Fortuna Düsseldorf II | 0-2 | 2 - 4 points |
| 12/03/22 14:00 | 12/03/22 14:00 | SV Lippstadt 08 | SV Straelen | 1-2 | 2 - 4 points |
| 12/03/22 14:00 | 12/03/22 14:00 | KFC Uerdingen | Rot-Weiss Ahlen | 1-1 | 2 - 4 points |
| 12/03/22 14:00 | 12/03/22 14:00 | 1. FC Cologne II | FC Wegberg-Beeck | 4-1 | 2 - 4 points |
| 12/03/22 14:15 | 12/03/22 14:15 | Bonner SC | Bor. Mönchengladbach II | 1-1 | 2 - 4 points |
| 13/03/22 14:00 | 13/03/22 14:00 | FC Schalke 04 II | Wuppertaler SV | 0-4 | 2 - 4 points |
| 05/04/22 19:30 | 05/04/22 19:30 | Rot-Weiss Oberhausen | Rot-Weiss Essen | 1-1 | 2 - 4 points |
| 19/04/22 19:00 | 19/04/22 19:00 | Preußen Münster | SC Fortuna Cologne | 1-0 | 2 - 4 points |